Chemistry search without the enterprise price tag

Saguaro Chem is a chemical and reaction database for searching experimentally reported chemistry from peer-reviewed journals and patents. Search compounds, reactions, synthetic procedures, and characterization details by chemical structure, substructure, similarity, or bibliographic metadata.

Saguaro Chem indexes data from over 13 million reaction passages — individual text segments extracted from source literature that describe a reaction. Not all data types are available for every record. Some entries include the raw source passage, others include annotated procedures, reaction schemes, or characterization data, and some may only contain the extracted compounds and their roles in the reaction. The specific data available depends on the source document and extraction quality.

Saguaro Chem indexes experimental reaction information from 30+ peer-reviewed journals, including: ACS Catalysis, ACS Chemical Neuroscience, ACS Medicinal Chemistry Letters, ACS Omega, ACS Pharmacology & Translational Science, Advanced Synthesis & Catalysis, Angewandte Chemie International Edition, Asian Journal of Organic Chemistry, Beilstein Journal of Organic Chemistry, ChemCatChem, ChemMedChem, Chemical Communications, Chemical Science, Chemistry – A European Journal, Chemistry – An Asian Journal, Chinese Journal of Chemistry, European Journal of Organic Chemistry, Green Chemistry, Journal of Medicinal Chemistry, Molbank, Molecules, Nature Chemistry, Nature Synthesis, New Journal of Chemistry, Organic & Biomolecular Chemistry, Organic Chemistry Frontiers, Organic Letters, Synlett, Synthesis, Tetrahedron, Tetrahedron Letters, The Journal of Organic Chemistry.

Yes. Saguaro Chem currently indexes reaction information from USPTO granted patents. We are actively working to expand patent coverage to additional patent offices in future updates.

Yes. Saguaro Chem supports exact-match, substructure, and similarity search across compounds and reactions. You can enter a SMILES string, InChI, or chemical name, or draw a structure directly in the search interface using the built-in Ketcher editor.

Yes. Saguaro Chem extracts and indexes stepwise experimental procedures directly from source literature. Each procedure includes reagents, quantities, reaction conditions, and workup steps where reported, presented in a clean, structured format so you can reproduce the synthesis in the lab.

Search results include yields, reaction conditions, full bibliographic details (DOI, title, author, journal), and links to the original source document. Where available, characterization data such as NMR, IR, mass spectrometry, melting points, and optical rotation are also included.

Saguaro Chem sources reactions from USPTO granted patents and 30+ top peer-reviewed journals, and we are continually expanding coverage. New content is added to the database on an ongoing basis, if a specific source is missing you can request it.

Yes. Saguaro Chem is designed for researchers who need reaction and structure search capabilities without the cost or access barriers of traditional enterprise databases. You get experimental context from peer-reviewed journals and patents at a fraction of the price.

No. Saguaro Chem is an affordable chemical reaction database that you can access without an institutional subscription. Sign up individually or as a small team in under two minutes with just a credit card.

Yes. Saguaro Chem is priced for independent researchers, students, and small teams who need a professional chemistry database without an enterprise license. We offer transparent monthly plans with no price increases without 90 days notice and no retention loops when you cancel.

Sign up for a free 7-day trial in under two minutes. No institutional affiliation required. Once your account is active, you can start searching the reaction database immediately.

No. For reactions sourced from academic articles, Saguaro Chem does not display the source text or distribute PDFs. Instead, we try to show as much non-passage context as possible in the form of a reaction scheme and an annotated procedure, along with characterization details where available — though the specific data types available may vary by entry and are not necessarily comprehensive. Each entry links back to its original source so you can access the complete publication or supplementary information on the publisher's website.

Yes. Unlike academic articles, Saguaro Chem does display the raw source passages from patents for reactions sourced from patent literature. Each patent-sourced entry includes the relevant excerpt from the original patent text alongside the structured data, so you can read the procedure, conditions, and characterization details exactly as they appear in the patent.

We are open to discussing raw data access for both academic and commercial use cases. Whether you are a researcher looking to support a publication or a company interested in licensing the dataset, we encourage you to reach out via our contact page or at contact@denovochem.com to discuss your needs.

Yes. We never log the contents of your search queries — no SMILES strings, no structure drawings, no text searches are ever recorded. Our infrastructure is hosted on SOC 2 Type II compliant hosting (Railway), accounts support two-factor authentication via Clerk, and IP addresses are truncated and hashed before any storage.

De Novo Chem is not independently SOC 2 certified. We use SOC 2 Type II compliant vendors for our hosting and authentication infrastructure, which means your data is protected by enterprise-grade security practices at the infrastructure level. We are committed to maintaining strong security standards.

All payments are handled by our authentication provider, Clerk, which uses Stripe as its underlying payment processor. De Novo Chem never sees, stores, or handles your credit card information — the entire payment flow is managed by Clerk and Stripe.

No. Saguaro Chem is a purely digital search and discovery service. We do not sell, distribute, or broker chemicals, pharmaceuticals, or laboratory supplies of any kind.